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Home
About Us
Mission and Values
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Science
Pipeline
Therapeutics
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Rivoceranib
Camrelizumab
Publications and Presentations
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Press Releases
Events
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Contact Us
Search
Search
Home
About Us
Mission and Values
Leadership
Executive Leadership Team
Board of Directors
Scientific Advisory Board
Science
Pipeline
Therapeutics
Lirafugratinib
Rivoceranib
Camrelizumab
Publications and Presentations
News
Press Releases
Events
Investors
Partnering
Careers
Contact Us
Publications and Presentations
OncoDaily Medical Journal:
Association of Alpha-Fetoprotein and Clinical Outcomes in Patients with Unresectable Hepatocellular Carcinoma Treated with First-Line Camrelizumab Plus Rivoceranib vs Sorafenib: Post Hoc Exploratory Analysis of the CARES-310 Trial
International Liver Cancer (ILCA) 2026 Annual Conference:
Younger Age and Clinical Outcomes in Patients with Unresectable Hepatocellular Carcinoma Treated with Camrelizumab +
Rivoceranib vs Sorafenib (CARES-310)
ASCPT 2026:
The Mass Balance and Metabolic Profile of Lirafugratinib in Healthy Male VolunteersComparative Biochemical Kinase Activity Analysis Identifies Lirafugratinib as a Highly Selective FGFR2 Inhibitor
AACR 2026:
Comparative Biochemical Kinase Activity Analysis Identifies Lirafugratinib as a Highly Selective FGFR2 Inhibitor
2026 ASCO
®
Annual Meeting:
A Phase 2, open-label, single-arm study of lirafugratinib in patients with previously treated, unresectable, locally advanced, or metastatic solid tumors (excluding cholangiocarcinoma) with FGFR2 fusion or rearrangement
2026 AACR
®
Annual Meeting:
Comparative Biochemical Kinase Activity Analysis Identifies Lirafugratinib as a Highly Selective FGFR2 Inhibitor
2026 ASCO
®
GI Annual Meeting:
Efficacy and safety of lirafugratinib in patients with FGFRi-naïve cholangiocarcinoma harboring FGFR2 fusions/rearrangements
ASCO GI 2025:
Clinical outcomes of camrelizumab + rivoceranib vs sorafenib (CARES-310) as first-line treatment for patients with unresectable hepatocellular carcinoma (uHCC) of viral and non-viral etiology
2025 ESMO
®
Annual Meeting:
CARES-310 – Clinical benefit of camrelizumab + rivoceranib in unresectable hepatocellular carcinoma patients with macrovascular invastion and extrahepatic spread
2025 ESMO
®
GI Annual Meeting:
Cares-310 – Association of alpha-fetoprotein (AFP) and clinical outcomes in patients with unresectable hepatocellular carcinoma (uHCC) treated with camrelizumab + rivoceranib vs sorafenib
ESMO 2024:
A Phase 1 Study of Rivoceranib Combined with Nivolumab in Patients with Unresectable or Metastatic Cancer
AACR 2024:
Effect of Rivoceranib Administered as 200 mg Once Daily on the Pharmacokinetics of CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4 Substrates
ESMO 2024:
Analysis of Antidrug Antibodies (ADA) to Camrelizumab in CARES-310: The Pivotal Phase 3 Study of Camrelizumab + Rivoceranib in Unresectable Hepatocellular Carcinoma (uHCC)
ESMO 2024:
Quality-adjusted Time Without Symptoms or Toxicity (Q-TWiST) Analysis to Assess the Impact of Treatment With Camrelizumab + Rivoceranib (cam+rivo)
on Quality of Life vs Sorafenib in Patients With Unresectable Hepatocellular Carcinoma: Study CARES-310
52nd Annual Meeting of Korean Cancer Association:
Post hoc analysis of efficacy and safety between US and Korean patients treated with rivoceranib for recurrent or metastatic adenoid cystic carcinoma
Cancer Research and Treatment:
Phase 1/2a Study of Rivoceranib, a Selective VEGFR-2 Angiogenesis Inhibitor, in Patients with Advanced Solid Tumors
Gastric Cancer: Rivoceranib, a VEGFR-2 inhibitor, monotherapy in previously treated patients with advanced or metastatic gastric or gastroesophageal junction cancer (ANGEL study):
an international, randomized, placebo-controlled, phase 3 trial
Liver Cancer: Impact of age on patient-reported outcomes with first-line camrelizumab plus rivoceranib versus sorafenib in adults with unresectable hepatocellular carcinoma:
Post hoc analyses of the CARES-310 open-label, randomized, phase 3 trial
Clinical Pharmacokinetics: Effect of Rivoceranib 200 mg Once Daily on the Pharmacokinetics of a Cocktail Probe Substrate of Cytochrome P450 Enzymes:
A Phase I Trial in Healthy Volunteers
2024 ASCO
®
Annual Meeting
: Camrelizumab plus rivoceranib vs sorafenib as first-line therapy for unresectable hepatocellular carcinoma (uHCC): Final overall survival analysis of the phase 3 CARES-310 study
Role of neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte-ratio (PLR) in unresectable hepatocellular carcinoma (uHCC): Subgroup analysis of patients treated with camrelizumab (cam) + rivoceranib (rivo) in the CARES-310 trial.
The Lancet 2023: Camrelizumab Plus Rivoceranib Versus Sorafenib as First-Line Therapy for Unresectable Hepatocellular Carcinoma (CARES-310): a Randomised, Open-Label, International Phase 3 Study
2024 ASCO
®
Gastrointestinal Cancers Symposium: Patient-Reported Outcomes (PROs) <65 or ≥65 Years Old From CARES-310 Camrelizumab + Rivoceranib vs Sorafenib as First-Line Treatment for Patients With Unresectable Hepatocellular Carcinoma
2024 ASCO
®
Gastrointestinal Cancers Symposium: Impact of Baseline Liver Function on Survival Outcomes in Patients With Unresectable Hepatocellular Carcinoma (uHCC) Treated With Camrelizumab + Rivoceranib vs Sorafenib: A Post Hoc Analysis of Study CARES-310
ESMO 2023: Phase 1b/2 Open-label Study to Evaluate the Safety, Tolerability, and Efficacy of Rivoceranib Plus Trifluridine/Tipiracil in Patients With Previously Treated Metastatic Colorectal Cancer
Clinical Cancer Research 2023: A Phase II Trial of Rivoceranib, an Oral Vascular Endothelial Growth Factor Receptor 2 Inhibitor, for Recurrent or Metastatic Adenoid Cystic Carcinoma
Cancer Chemotherapy and Pharmacology 2023: Comparative Biochemical Kinase Activity Analysis Identifies Rivoceranib as a Highly Selective VEGFR2 Inhibitor
2023 ASCO
®
Annual Meeting: Updated Results From a Phase 2 Study of the Oral Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Inhibitor Rivoceranib for Recurrent or Metastatic (R/M) Adenoid Cystic Carcinoma (ACC)
2023 ASCO
®
Annual Meeting: Updated Results From a Phase 2 Study of the Oral Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Inhibitor Rivoceranib for Recurrent or Metastatic (R/M) Adenoid Cystic Carcinoma (ACC)
2023 ASCO
®
Annual Meeting: Phase 1, Randomized, Open-Label, Single-Dose, Crossover Study to Evaluate the Bioequivalence of Four Formulations of Oral Rivoceranib Tablets in Healthy Subjects
AACR 2023: Comparative Biochemical Kinase Activity Analysis Identifies Rivoceranib as a Highly Selective VEGFR-2 Inhibitor
AACR 2023: Effect of Rivoceranib on the Pharmacokinetics of Cytochrome P450 Enzyme Substrates: A Phase 1 Trial in Healthy Volunteers
ESMO 2022: Phase 1 Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of Rivoceranib Plus Paclitaxel in Advanced Gastric or Gastroesophageal Junction Cancer
2022 ASCO
®
Annual Meeting: A Phase 2 Study of the Oral Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Inhibitor, Rivoceranib, for Recurrent or Metastatic (R/M) Adenoid Cystic Carcinoma (ACC)
Gynecologic Oncology: Phase 3 Publication of Efficacy & Safety Results Comparing Paclitaxel Micellar & Cremophor EL-Paclitaxel
2020 ASCO
®
Annual Meeting: A Phase 2 Open-Label, Multicenter Study to Evaluate Efficacy and Safety of Rivoceranib in Recurrent or Metastatic Adenoid Cystic Carcinoma
2019 ASCO
®
-SITC Clinical Immuno-Oncology Symposium: Phase I Study to Evaluate the Safety and Efficacy of Rivoceranib (Apatinib) and Nivolumab in Patients with Unresectable or Metastatic Cancer
AACR 2018: Synergistic Tumor-Suppressive Effect of Apatinib (Rivoceranib), a Selective VEGFR-2 Inhibitor, in Combination With Immunotherapy in a Syngeneic Murine Lung Cancer Model
ACCP 2017: A Phase I Study to Evaluate the Pharmacokinetics of a Single Dose of Apatinib Mesylate (YN968D1) Tablets in Healthy Male Caucasian, Japanese, and Chinese Subjects
2017 ASCO
®
Annual Meeting: A Prospective, Randomized, Double-Blinded, Placebo-Controlled, Phase III Study to Evaluate the Efficacy and Safety of Apatinib Plus Best Supportive Care (BSC) Compared to Placebo Plus BSC in Patients With Advanced or Metastatic Gastric Cancer: The ANGEL Study
ESMO 2016: A Phase II Study of Apatinib, a Highly Selective Inhibitor of VEGFR-2, in Patients With Metastatic Solid Tumors Without Standard Treatment Options